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El bupropión actúa sobre dopamina y noradrenalina — no sobre serotonina. Esa diferencia de mecanismo explica por qué tiene indicaciones que ningún otro antidepresivo tiene: depresión con fatiga, cesación tabáquica, disfunción sexual inducida por ISRS y uso off-label en TDAH con evidencia clínica. El QF Manu Valladares explica el mecanismo con analogía simple y las cinco situaciones clínicas donde esa diferencia importa. En este video aprenderás: → Por qué dopamina y noradrenalina explican todo l
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