Autism and brain aging are more connected than you think 🧠✨ This study explores how the gene MEF2C regulates transcriptional and epigenetic activity in human microglia—key immune cells in the brain—and how these changes may influence both autism risk and age-related neurological disease. By mapping MEF2C’s targets, researchers show how gene regulation in microglia impacts inflammation, brain development, and cellular function. This helps bridge neurodevelopmental and neurodegenerative condition
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Here is a reminder of the potential of Gene Therapy in #RettSyndrome These mice are male "Rett" mice. The mouse moving around was given gene therapy treatment and received healthy MECP2 gene. The immobile mouse did not receive treatment. The video was taken 4 weeks after treatment. This work was done in the lab of Gail Mandel in collaboration with Adrian Bird and was financially supported by Reverse Rett via RSRT. #RettSyndrome #ReverseRett #ChangeisPossible https://www.youtube.com/watch?v=eBxPU
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