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Case Study 207 - Huntington’s Disease Huntington’s disease is a hereditary neurodegenerative disorder that slowly affects movement, cognition, and behavior. It’s caused by a CAG repeat expansion in the HTT gene, leading to progressive damage of the basal ganglia - the brain region that helps coordinate movement and emotional regulation. Patients often present with a combination of: • Chorea (involuntary, dance-like movements) • Personality or mood changes such as irritability, depression, or imp
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