Classify Rx on Instagram: "🎯 Fluconazole (Best CNS Penetration) 📍 Excellent CSF levels: Achieves 70-80% of serum concentration in CSF - hydrophilic properties allow superior BBB crossing compared to other azoles 📍 Primary use: First-line for cryptococcal meningitis (after amphotericin B induction), candida CNS infections, coccidioidal meningitis - oral bioavailability ~90% 🎯 Voriconazole (Good CNS Penetration) 📍 Moderate CSF levels: Achieves ~50% of serum concentration in CSF - lipophilic b
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