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cap.org
The Expanding Role of Cell‑Free DNA in Pathology
NORTHFIELD, Ill. (April XX, 2026) — Cell‑free DNA (cfDNA) is rapidly expanding beyond its established roles in oncology and prenatal screening, with growing relevance for transfusion medicine and...
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Prenatal screening for fetal aneuploidy can be performed by analyzing cell-free DNA (cfDNA) in maternal blood, which derives from both maternal and placental sources during pregnancy. Placental cfDNA is rapidly cleared from the maternal circulation after delivery, thus cfDNA test results in future pregnancies are not affected by prior pregnancies.No result rates generally fall between 1 and 3 percent. Maternal plasma must contain an adequate amount of fetal cfDNA (fetal fraction) to obtain a rel
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A cell-free DNA blood test could be an option for patients who repeatedly decline colonoscopy or stool testing for #ColorectalCancer screening. #ASCO25 Read the new JAMA Original Investigation to learn more. https://ja.ma/4jAEkGC | JAMA
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Cell-free DNA (cfDNA) or “circulating DNA” are tiny pieces of DNA that moves freely in the bloodstream, released by cells as they die. It can come from healthy cells, tumors, or, during pregnancy, from the placenta. We can look at circulating DNA through blood tests to check for diseases like cancer or to monitor a baby’s health in the womb. The test, called non-invasive prenatal screening or testing (NIPT or NIPS), looks at tiny pieces of DNA in the mom’s blood to check for specific differences
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