New therapy that targets and destroys tau tangles is a promising …
Sep 16, 2024 · Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
How Tau tangles form in the brain - MIT News
Jul 14, 2023 · MIT chemists have gained insight into how Tau tangles form in the brains of people with Alzheimer’s disease. They also identified a potential target for drugs that could interfere with tangle formation.
TYK2 enzyme alters tau protein that contributes to Alzheimer's …
1 day ago · Preventing Tyr29 phosphorylation attenuates tau pathology, but TYK2 expression aggravates pathology in P301S mice. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01777-2
TauRx sees path to FDA filing for tau-targeting Alzheimer's drug
3 days ago · TauRx Pharma's effort to bring a tau-targeting drug for Alzheimer's disease (AD) to market has been a marathon, with a number of setbacks over the years, but the company reckons it may finally...
A Blood Test Accurately Diagnosed Alzheimer’s 90% of the Time, …
Jul 28, 2024 · The new study used a blood test that focuses on a form of a protein called tau that sprouts into tangles in the brains of people with Alzheimer’s.
Newly identified genetic variant protects against Alzheimer’s
May 15, 2023 · Researchers identified a first-of-its-kind patient with a genetic predisposition for early-onset Alzheimer’s disease who remained cognitively intact more than two decades beyond the expected age of memory impairment.
Neuron model paves way for new Alzheimer’s therapies
Apr 8, 2024 · Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain – a process that drives cognitive decline in Alzheimer’s disease and frontotemporal dementia.
Researchers find the roots of tau tangles in Alzheimer’s disease
Nov 3, 2023 · An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer’s disease, researchers from Yale School of Medicine and Johns Hopkins University report.
FDA Approves First Drug to Image Tau Pathology in Patients Being ...
May 28, 2020 · Today, the U.S. Food and Drug Administration approved Tauvid (flortaucipir F18) for intravenous injection, the first drug used to help image a distinctive characteristic of Alzheimer’s disease in...
Chemists reveal how tau proteins form tangles | MIT News ...
May 27, 2022 · A new study from MIT chemists has revealed how two types of tau proteins, known as 3R and 4R tau, mix together to form these tangles. The researchers found that the tangles can recruit any tau protein in the brain, in a nearly random way.