Nov 25, 2024 · Assessing inflammation with vitamin B supplement. The University of Copenhagen launched a single-center trial (NCT04990869) at the Respiratory Research Unit at Bispebjerg Hospital in Copenhagen to test nicotinamide riboside against a placebo for its potential as a COPD treatment. The study included 40 adults, mean age 71.9, who had COPD, a history of heavy smoking, and low numbers of ...

Sep 30, 2024 · In the U.S., the expansion of Dupixent’s label to include COPD brings the number of approved indications up to six, adding to its use as a treatment for atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, and prurigo nodularis — all driven in part by type 2 inflammation. “Dupixent has already shown it can revolutionize the treatment paradigm ...

Sep 3, 2020 · So, researchers based at the Maastricht University in the Netherlands designed the Morphine for Treatment of Dyspnea in Patients With COPD (MORDYC) Phase 4 study (NCT02429050).It investigated whether regular, low-dose, oral sustained-release morphine improved health in COPD patients with moderate-to-very-severe chronic breathlessness.

Sep 16, 2024 · That’s according to top-line data from a Phase 3 clinical trial called MATINEE (NCT04133909) announced by GSK in a company press release.The study tested mepolizumab against a placebo in adults with COPD and type 2 inflammation, which is marked by high blood counts of eosinophils, a type of immune cell.

Oct 14, 2024 · In an oral presentation titled “Ensifentrine Improved Lung Function, Symptoms, and Quality of Life Regardless of COPD Severity,” Jessica M. Bon, MD, of Wake Forest University School of Medicine, shared Ohtuvarye’s effects in subgroups of ENHANCE participants stratified by COPD severity. The results showed that Ohtuvaryre led to significant improvements in lung function after three months ...

Oct 28, 2024 · The U.S. Food and Drug Administration (FDA) has approved Abrysvo, a vaccine that protects against lung infections caused by the respiratory syncytial virus — commonly known as RSV — for adults as young as 18 with chronic obstructive pulmonary disease (COPD) or other conditions that increase the risk of such infections.

Oct 30, 2024 · Just how long can a person have low oxygen saturation before damage occurs? The answer is unknown. I feel that any amount of time with low oxygen saturation is too long, as expressed in a 2019 COPD News Today article, “Oxygen Manifesto, Part 1: Advice from 3 Respiratory Therapists.”. I’m not sure my oxygen saturation is staying above 88% while using my portable concentrator because I don ...

Sep 23, 2024 · The voice of people with chronic obstructive pulmonary disease (COPD) becomes more pitched and sounds breathy or hoarse at the early stages of disease exacerbations, which are episodes when symptoms suddenly worsen, according to a pilot study where 28 patients were asked to record their voices every day for about three months.

Mar 18, 2024 · The THARROS study (NCT06283966) is expected to enroll up to 5,000 COPD patients, ages 40 to 80, with a risk of cardiopulmonary complications at more than 650 centers in the U.S., Canada, and countries in Europe, South America, and Asia.. Participants will be randomly assigned to receive either Breztri Aerosphere or to AstraZeneca’s dual-combination Bevespi Aerosphere (glycopyrronium ...

Jul 3, 2023 · Better FEV1 seen with ensifentrine’s use in ENHANCE-1 and -2 studies “The ENHANCE trials demonstrate ensifentrine’s outstanding ability to reduce the rate and risk of COPD exacerbations and to provide meaningful improvements in lung function and symptoms in a broad COPD population,” Antonio Anzueto, MD, the study’s first author and a professor of medicine and pulmonary section chief ...