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  1. Everything You Should Know About NSCLC - WebMD

    Dec 5, 2025 · Learn about the role of EGFR mutations in NSCLC, how it is treated, and which groups are most at risk.

  2. EGFR and Lung Cancer - American Lung Association

    Dec 9, 2025 · EGFR, which stands for epidermal growth factor receptor, is a protein located on the surface of cells that helps them grow. When there is a mutation, or change, in the EGFR …

  3. EGFR Positive Lung Cancer - Verywell Health

    3 days ago · An EGFR mutation causes rapid cell growth, which helps lung cancer spread. Gene testing can identify it and help tailor lung cancer treatment.

  4. EGFR Mutation and Lung Cancer: What is it and how is it treated?

    Learn more about the EGFR mutation, how to detect it, and what are your treatment options for EGFR-positive lung cancer.

  5. Rare epidermal growth factor receptor (EGFR) mutations in …

    In this review, we describe the structural and mechanistic features of rare EGFR mutations in NSCLC and discuss the preclinical and clinical evidence for EGFRi response for individual …

  6. What Does EGFR+ Lung Cancer Mean? | LungCancer.net

    May 22, 2025 · EGFR is a protein that helps cells grow. However, a change (mutation) in the gene for EGFR can cause cells to grow too fast. This abnormal growth can cause cancer. 1. Having …

  7. EGFR Mutation and Lung Cancer: Your FAQs - Healthline

    Aug 16, 2021 · EGFR-positive lung cancer means that there’s a change in part of the tumor’s DNA. This change, known as a mutation, may be helping it grow. This is common among …

  8. EGFR Mutation Types: What They Are and Why They Matter

    Jul 27, 2025 · In the context of EGFR, a mutation causes the EGFR protein to become overactive, behaving as if it is constantly “on” even without external signals. This persistent activation …

  9. Chen-Huang Center for EGFR Mutant Lung Cancers

    In 2004, Dana-Farber investigators discovered that a subset of lung cancers exhibited mutations in the EGFR gene. These mutations were predictive of the clinical efficacy of epidermal growth …

  10. The changing treatment landscape of EGFR-mutant non-small-cell …

    Nov 29, 2024 · In this Review, we describe the current first-line treatment options for EGFR -mutant NSCLC, provide an overview of the mechanisms of acquired resistance to third …