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  1. Syphilis: Screening and diagnostic testing - UpToDate

    Aug 21, 2024 · Patients may seek evaluation for symptoms or signs of primary infection (eg, chancre), secondary infection (eg, diffuse rash), or tertiary infection (eg, symptoms of aortic …

  2. CDC Laboratory Recommendations for Syphilis Testing, United …

    Feb 6, 2024 · This report provides new CDC recommendations for tests that can support a diagnosis of syphilis, including serologic testing and methods for the identification of the …

  3. Syphilis Tests: MedlinePlus Medical Test

    If your screening test results are positive, it means you have antibodies that may be from a syphilis infection. Your provider will likely order a second test to confirm whether or not you …

  4. Screening for Syphilis | Guidelines | JAMA | JAMA Network

    Sep 27, 2022 · What Tests Are Used to Screen for Syphilis? Screening for syphilis is typically performed with blood testing to detect antibodies indicating possible infection with syphilis. If …

  5. Syphilis Tests & Diagnosis: VDRL, RPR, EIA, TPPA, & More - WebMD

    Apr 30, 2025 · Only your doctor can know for sure whether you have syphilis. The USPSTF recommends that anyone who is at increased risk for infection undergo screening. Your doctor …

  6. Syphilis - Diagnosis and treatment - Mayo Clinic

    You may be able to use a test that's available without a prescription, sometimes called an at-home test, to see if you have syphilis. If that test shows you have syphilis, you'll need to see a …

  7. CDC-Compliant Syphilis Screening | Early Detection | Labcorp

    The CDC-recommended algorithms for the screening and diagnosis of syphilis include both treponemal and non-treponemal assays. Labcorp offers both the Reverse syphilis screening …

  8. Syphilis: Laboratory Support for Screening, Diagnosis, and …

    Prompt and accurate diagnosis of syphilis is important because successful treatment eradicates the bacteria and can resolve many symptoms of the disease. This Clinical Focus provides an …

  9. Syphilis Infection in Nonpregnant Adolescents and Adults: Screening

    Sep 27, 2022 · Traditional screening algorithm: Screen with an initial nontreponemal test (eg, Venereal Disease Research Laboratory [VDRL] or rapid plasma reagin [RPR] test). If positive, …

  10. Without treatment, syphilis can damage the brain, nerves, eyes, and cardiovascular system. Screening and follow-up treatment can cure syphilis and prevent complications.