Hypertrophic cardiomyopathy (HCM) is a heterogeneous disorder with varying risks of clinical outcomes, including sudden cardiac death (SCD). We aimed to identify distinct phenotypes among patients ...

Increased left atrial pressure (LAP) contributes to dyspnea and heart failure with preserved ejection fraction in patients with atrial fibrillation (AF). The purpose of this study was to investigate ...

Here, we review recent mechanistic and clinical evidence suggesting an additional preventive strategy for patients at risk for AF and patients after thoracic and cardiac surgery, namely, treatment ...

Although overt atherosclerotic disease (especially when clinically symptomatic) is comparatively easy to see, its future development in an asymptomatic population is hard to foresee. Indeed, at the ...

Overweight or obesity results in a wide range of elevated risk factors and many fatal and nonfatal conditions. 4 Paradoxically, although we have witnessed decades in which heart disease and stroke ...

From the Department of Medicine, University of California San Diego, La Jolla. A crucially important point needs to be noted here: For whatever reasons, the Japanese have their lower cholesterol ...

BackgroundHIV is associated with elevated risk of heart failure (HF). Despite poor agreement between automated, administrative code–based HF definitions and physician‐adjudicated HF, no studies hav ...

BACKGROUND: Thromboembolic events, including myocardial infarction (MI) or stroke, caused by the rupture or erosion of unstable atherosclerotic plaques are the leading cause of death worldwide.

Cardiovascular health can be improved quickly through sound public health measures that have an impact at a population level. 3 Smoke-free workplaces and public places, comprehensive advertising bans, ...

Background—With wide availability of low-cost generics, primary prevention with statins has become less expensive. We projected the cost-effectiveness of expanded statin prescribing strategies using ...

Hypertension is the leading risk factor for cardiovascular disease worldwide. Patients with blood pressure (BP) response to dietary sodium reduction are referred to as “salt sensitive.” Salt ...

Heart failure (HF) is characterized by a progressive decline in cardiac function and represents one of the largest health burdens worldwide. Clinically, 2 major types of HF are distinguished based on ...