San Francisco 49ers head coach Kyle Shanahan discusses how 49ers running back Christian McCaffrey's injury setback has forced ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

J.B. Long examines how both the Los Angeles Rams and San Francisco 49ers are dealing with significant injuries on the ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

The 49ers need a backup running back. That's why they traded up for Isaac Guerendo in Round 4 this year. Just in case someone gets injured. And currently, both ...

Speaking to NBC Sports Bay Area's Greg Papa on "49ers Game Plan," Kyle Shanahan explained why the offense won't change ...

SANTA CLARA, Calif. (AP) — The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game ...

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

Head coach Kyle Shanahan shared the final injury report ahead of the 49ers Week 3 matchup and discussed the team's ...

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

The San Francisco 49ers provided injury updates on Charvarius Ward, Nick Bosa and George Kittle ahead of Week 3 vs. the Los ...