But when safety Kirby Joseph of Detroit picked off Purdy twice, with the 49ers unable to reciprocate against Goff or force a ...

T he 49ers lost another game after holding a first-half lead. Say what you want about the matchup being meaningless. It was, ...

Nick Bosa appreciates going up against the best of the best. The 49ers defensive end recorded two sacks in San Francisco's 40-34 loss to the Detroit Lions on "Monday Night Football" at Levi's Stadium, ...

Chargers defensive end Morgan Fox was mic'd up for the Bolts' dominant win vs Drake Maye and the New England Patriots. This win sealed the path toward clinching playoffs for Justin Herbert and the ...

The San Francisco 49ers dropped their record to 6-10 after a 40-34 loss against the Detroit Lions in Week 17. Today, Pro ...

The 49ers just lost 40-34 to the Detroit Lions. Here are the 49ers' grades for this emabarrassing performance. QUARTERBACK: C-MINUS Brock Purdy w ...

San Francisco 49ers head coach Kyle Shanahan recapped the team's 40-34 loss to the Detroit Lions, evaluated the 49ers performance on "Monday Night Football" and shared injury updates on QB Brock Purdy ...

The Detroit Lions got their revenge on the San Francisco 49ers. Here are winners and losers from the Week 17 Monday Night Football clash.

The standings might not have been affected, but the 49ers and Lions delivered one of the season’s most entertaining games. Of ...

The San Francisco 49ers gave the Detroit Lions all they could handle for much of their showdown at Levi's Stadium in Santa ...

The 49ers (6-10) could not keep pace with the playoff-bound Detroit Lions (14-2) and lost 40-34 in Monday’s Levi’s Stadium ...

Well, it wasn’t as ugly as it could’ve been. The San Francisco 49ers fell to the Detroit Lions in an NFC championship game ...