A switch folded from DNA holds its position while heat shakes it, flips on command, and in the best cases kept working ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

Learn how researchers at St. Jude, led by Hai Dao, PhD, discovered the mechanisms behind PARP1-mediated DNA repair.

Called Cas12a2, the CRISPR system had some distinctive properties. Rather than editing cells’ DNA when prompted by a guide RNA, as CRISPR-Cas9 does, Cas12a2 indiscriminately shreds it, ultimately ...

Complete lesson for Pearson Edexcel IAL Biology Topic 2: DNA replication, DNA polymerase and Meselson–Stahl, with real WBI11 questions and mark schemes. Save precious planning time with a complete, ...

More than two decades after scientists first sequenced the entire human genome — all 3 billion “letters,” or base pairs, of DNA code — the meaning of much of this code remains a mystery. While an ...

Teresa Shu-Fong Wang, PhD, professor emeritus of pathology at Stanford Medicine, died June 7 at her home in Palo Alto, California. She was 88. Wang, who joined the Stanford School of Medicine in 1969, ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...

It’s tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...