AT&T remains on track to achieve its net leverage target of net-debt-to-adjusted EBITDA in the 2.5x range by the first half of 2025 and intends to sustain this level through 2027.

Researchers have developed ALA-CART, a next-generation therapy aimed at improving outcomes for patients with resistant cancers. Scientists have supercharged CAR-T therapy, making it more powerful ...

During primary HIV infection (PHI), many cells of the immune system show signs of extensive activation and a progressive loss of resting subsets (1). Several T-cell subsets can be defined by their ...

This study used Wistar rats (7 weeks of age; 222 ± 10 g; half male and half female) at the beginning of the study. The rats were acclimatized for 10 days before the experiment, and they were kept in ...

T cells play a crucial role in the adaptive immune system’s defense against external invasion. To distinguish between self and non-self, T cells use their T cell receptors (TCRs) to recognize ...

Background: Immune non-responders (INR) are HIV+, ART-controlled (>2 yrs) people who fail to reconstitute their CD4 T cell numbers. Systemic inflammation and markers of T cell senescence and ...

Little is known about the metabolic regulation of rare cell populations because most metabolites are hard to detect in small numbers of cells. We previously described a method for metabolomic ...

We compared the workflow of the Beckman Coulter automated Aquios CL flow cytometer, using AQUIOS Tetra software, to a single platform method using the Beckman Coulter TQ-Prep lysing system with ...