Germinal centers are machines of rapid evolution. Germinal centers are tiny clusters in the lymph nodes that refine antibodies through proliferation and mutation to create high-affinity B cells that ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Dr. Andrés Hidalgo has discovered a ...

We spoke with Mark Boothby, Professor of Immunology at Vanderbilt University, about his experience publishing with eLife.

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...

Researchers have discovered that immune cell levels in cancer patients can predict survival rates and treatment outcomes ...

Two years after Neil Armstrong walked on the Moon, US president Richard Nixon declared a new frontier in American scientific ...

Explore diffuse large B-cell lymphoma — symptoms, causes, diagnosis, treatment options, and prevention. Learn about its types ...