CAR T-cell therapy tricks cancer cells with decoy, increases treatment efficiency in B-cell acute lymphoblastic leukemia
B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...
The Scientist8y
Infographic: Single-Cell CRISPR Screens
A library of guide RNAs—each targeting a unique gene for CRISPR-based interference and carrying a unique barcode sequence—is introduced into a population of cells at a concentration that results in ...
Built-in safeguard in B cell populations could impact vaccine design
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies ...
Healio6d
‘Landmark’ B-cell depletion data offer hope to patients with IgG4-related disease
Last November, results from the MITIGATE trial made headlines at ACR Convergence 2024 with positive phase 3 trial data for inebilizumab, an IgG1 monoclonal antibody targeting CD19, in patients with ...