Drivers traveling a portion of Interstate 24 westbound in Massac County may want to find an alternate route on Friday morning ...

(CNN) - Walgreens is recalling more than 41,000 bottles of nasal spray because they may be contaminated with bacteria. The ...

This afternoon will be sunny and a little warmer, but still chilly in the upper 30s and low 40s. Clouds will begin filtering ...

The charges against the man who authorities say shot two National Guard members have been upgraded to first-degree murder after one of the soldiers died.

A “polar” run through the Christmas lights in Cape County Park South will raise money for the athletes of Special Olympics ...

A downtown Cape Girardeau business opened its doors to first responders and those in need, offering a free holiday meal as a ...

In the spirit of Thanksgiving, one Cape Girardeau church spent the morning making sure no one went without a holiday meal.

A fiery MD-11 plane crash on Nov. 4 in Louisville, Kentucky, killed 14 people and injured at least 23 when the left engine ...

An Afghan national has been accused of shooting two West Virginia National Guard members just blocks from the White House.

Black Friday has become something of an anachronism in the e-commerce era. The day after Thanksgiving marks the official ...

Police said on Friday, Nov. 21, just before 7:30 p.m., a shooting happened during their annual tree lighting event.

Strong lake effect snow bands are expected to dump several inches of snow across the Great Lakes region Thanksgiving Day.