gut.bmj

Blockade of transforming growth factor β upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in ...

1 Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK 2 Division of Infection, Inflammation and Repair, University ...
gut.bmj

Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort study

4 Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA 5 Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana, USA 6 Digestive Disease Center, ...
gut.bmj

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

1 Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité, Campus Benjamin Franklin, Berlin, Germany 2 Department of Clinical Physiology, Charité, Campus Benjamin Franklin, ...
gut.bmj

A simple AGED score for risk classification of primary liver cancer: development and validation with long-term prospective HBsAg-positive cohorts in Qidong, China

Correspondence to Professor Jianguo Chen, Department of Etiology, Qidong Liver Cancer Institute, Qidong People’s Hospital, Qidong 226200, China; chenjg{at}ntu.edu.cn and Professor Hong Tu, State Key ...
Gut

Acute abdomen after endoscopic treatment of caecal angiodysplasia

A 70-year-old woman with no significant comorbidities presented to the emergency department with a 3-day history of asthenia, ...
Gut

Rectal lesion with a submucosal tumour-like appearance in a middle-aged woman

A 49-year-old woman had a rectal lesion detected during a screening colonoscopy and was referred to our institution for ...
gut.bmj

Colon and rectal cancer survival in seven high-income countries 2010–2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project)

Objectives As part of the International Cancer Benchmarking Partnership (ICBP) SURVMARK-2 project, we provide the most recent estimates of colon and rectal cancer survival in seven high-income ...
gut.bmj

The Vienna classification of gastrointestinal epithelial neoplasia

BACKGROUND Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of oesophageal, ...
gut.bmj

The oral microbiota in colorectal cancer is distinctive and predictive

Correspondence to Dr Paul W O‘Toole, School of Microbiology & APC Microbiome Institute, University College Cork, 17 T12 YN60 Cork, Ireland; pwotoole{at}ucc.ie Background and aims Microbiota ...
gut.bmj

New artificial intelligence system: first validation study versus experienced endoscopists for colorectal polyp detection

To improve colorectal polyp detection, a new artificial intelligence (AI) system (GI-Genius, Medtronic) was trained and validated on a dataset of white-light endoscopy videos from a high-quality ...
gut.bmj

RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation

Objective Serrated polyps (hyperplastic polyps, sessile or traditional serrated adenomas), which can arise in a sporadic or polyposis setting, predispose to colorectal cancer (CRC), especially those ...
gut.bmj

Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks

3 College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA Objective Despite widespread use of antibiotics for the treatment of life-threatening infections and for research on ...