Gut

Rectal lesion with a submucosal tumour-like appearance in a middle-aged woman

A 49-year-old woman had a rectal lesion detected during a screening colonoscopy and was referred to our institution for ...
gut.bmj

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis

a Pediatric Gastroenterology and Nutrition, Department of Pediatrics, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands, b Pediatric Gastroenterology and Nutrition, ...
gut.bmj

Fukuoka criteria accurately predict risk for adverse outcomes during follow-up of pancreatic cysts presumed to be intraductal papillary mucinous neoplasms

Correspondence to Dr Suresh T Chari, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA; chari.suresh{at}mayo.edu Objective Fukuoka ...
Gut

Molecular and cellular consequences of tumour-autonomous IL-6 signalling in intrahepatic cholangiocarcinoma

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a ...
gut.bmj

PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury

Objectives Autoimmune hepatitis (AIH) is a severe necroinflammatory liver disease associated with significant mortality. Although loss of hepatocytes is generally recognised as a key trigger of liver ...
Gut

Comment on: Therapeutic inhibition of HBsAg and HBV cccDNA through a novel phased combination treatment: glycine and interferon-α

We read with great interest the recent study by Lin Huang and colleagues, which demonstrates that glycine supplementation ...
gut.bmj

Roseburia inulinivorans increases muscle strength

Background Gut bacteria have been implicated in a wide range of health conditions, yet their potential role in preventing and treating muscle-wasting disorders remains largely unexplored. Objective We ...
gut.bmj

Vonoprazan-based versus proton pump inhibitor-based therapy in Helicobacter pylori eradication: an updated systematic review and meta-analysis of randomised trials

We read the Maastricht VI/Florence consensus report published in GUT with great interest.1 The report suggested that vonoprazan-based therapy is superior, or not inferior, to conventional proton pump ...
Gut

Appearances can be deceiving: an ulcerated oesophageal lesion

An 82-year-old man with alcohol-related cirrhosis (Child-Pugh class B), complicated by portal hypertension and a history of partial gastrectomy with Billroth I reconstruction for duodenal ulcer ...
gut.bmj

Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks

3 College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA Objective Despite widespread use of antibiotics for the treatment of life-threatening infections and for research on ...
gut.bmj

Targeting MXD1 sensitises pancreatic cancer to trametinib

4 Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China 5 Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research ...
gut.bmj

Twenty-four-week anti-PD-1 antibody regimen promoted HBsAg reduction and concurrently enhanced HBV-specific T cell responses in patients with chronic hepatitis B

Background PD-1 blockade has emerged as a promising approach for functional cure of chronic hepatitis B (CHB). Objective This study aimed to evaluate the safety profile of anti-PD-1 antibody (αPD-1), ...