The panel examined components of existing and proposed HRD and genomic instability biomarkers, such as mutational signatures, loss of heterozygosity, mutations in homologous recombination ...

Results Across the 20 scenarios, the results showed that PRA was cost-effective compared with CRA using a £20 000 per QALY threshold in women with a GPV in PALB2 who have OC or BC+OC family history, ...

We're pausing our coverage for today, but will be back soon with more updates on the war in Ukraine. Here are the key lines from today: Ukrainian special forces destroyed two bombers at an airbase ...

PALB2 and RAD51C were included in the analysis as core-HR genes with BRCA1/2 as their genetic defects are associated with HR-deficiency signatures. 17,18 AlphaMissense classifies mutations as either ...

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The Triangle Business Journal features local business news about Raleigh/Durham. We also provide tools to help businesses grow, network and hire.

Triple-negative breast cancer (TNBC) was first described as a distinct disease entity 20 years ago. 1 Since that time, there has been tremendous effort invested in understanding the clinical features ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

Fanconi anemia is a rare inherited condition that can cause bone marrow failure, physical abnormalities, and an increased risk of some cancers. Symptoms include tiredness, infections, easy ...

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