The San Francisco 49ers are also dealing with a litany of injuries. In addition to Christian McCaffrey and Deebo Samuel both ...

San Francisco 49ers running back Christian McCaffrey will be eligible off the injured reserve after Week 6, but could still miss a pivotal Week 7 Super Bowl rematch with the Kansas City Chiefs.

Heading down to Southern California for the first time in the 2024 season, the San Francisco 49ers will be shorthanded when ...

San Francisco 49ers star tight end George Kittle is doubtful for Sunday's game at the Los Angeles Rams due to a hamstring ...

In a segment on "The Insiders", NFL Network insider Ian Rapoport: Herbert's ankle injury will make Bolts QB's Week 3 status a 'coaching decision' ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

J.B. Long examines how both the Los Angeles Rams and San Francisco 49ers are dealing with significant injuries on the ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

The 49ers need a backup running back. That's why they traded up for Isaac Guerendo in Round 4 this year. Just in case someone gets injured. And currently, both ...

SANTA CLARA, Calif. (AP) — The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game ...

"Nobody knows" when Christian McCaffrey will be ready to return from injured reserve, 49ers coach Kyle Shanahan said Sunday.