Drugs and other treatments can be quite effective at killing cancer cells, yet many fall short as they struggle to penetrate ...

In vivo, tumor-bearing mice that had the HIF1α-deleted in T cells did not respond to ICB therapy. The researchers then showed a way to overcome that resistance to ICB therapy. Elucidation of the ...

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple ...

How does one measure the anticancer activity of a vaccine? In mice the answer is straightforward: cancer-bearing mice are immunized and the results quantified by measuring tumor size and survival.

Intermittent fasting in mice enhances natural killer cells’ cancer-fighting abilities. To test the effects of fasting, the researchers withheld food from tumor-bearing mice for one day, then let them ...

The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, ...

Treating the tumor-bearing mice with IL-3 reduced tumor growth and metastasis. However, antibody depletion of CTLs reversed this effect, emphasizing the role of CTLs in IL-3-mediated tumor control. To ...

Mouse cells tweaked to produce the tardigrade protein incurred less DNA damage than unaltered cells — hinting at a new tool for cancer patient care.

Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current ...

Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body.

To test the therapeutic, the research team injected it into the peritoneal cavity of ovarian cancer-bearing mice and observed the impact on overall survival and the phenotype of cancer cells in the ...