Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and females.

Calcific aortic valve disease (CAVD), and ensuing severe aortic stenosis (AS), is the foremost valvular disorder of aging, yet preventive therapies are lacking. A better understanding of the molecular ...

Notch inhibits the differentiation of cardiomyocytes from mesoderm in embryos and embryonic stem cells ... canal, valve development, ventricular trabeculation and outflow tract remodelling.

Another investigational strategy being developed for HLHS patients is the injection of stem cells within the myocardium of the right ventricle. Recent innovations in tissue engineering and ...