One of the major challenges in tuberculosis (TB) management is to identify the different stages of Mycobacterium tuberculosis (Mtb) infection. Although a quarter of the global population is estimated ...

The drugs, sutezolid and delpazolid, have demonstrated strong antimicrobial activity and a notably better safety profile ...

Tuberculosis remains a major health challenge in South Africa, but professional nurse Nhlanhla Mofokeng is determined to change that through education, compassion, and community support.

Through the model, TN aims to reduce the average time for TB patients from diagnosis to getting admitted to the hospital ...

This assay combines a pair of high affinity monoclonal antibodies directed towards largely Mycobacterium tuberculosis -specific lipoarabinomannan epitopes 7–9 and a silver-amplification step 10 that ...

Researchers have identified two new drug families that block a key tuberculosis (TB) enzyme, offering hope for novel ...

A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

The high-temperature requirement A (HtrA) family of serine proteases has been shown to play an important role in the environmental and cellular stress damage control system in Escherichia coli.

This work describes the most extensive discovery and functional characterization of small regulatory RNAs (sRNAs) in Mycobacterium tuberculosis to date. We comprehensively define the sRNAs expressed ...

A new credit card-sized tuberculosis (TB) test, requiring no electricity, could revolutionize detection in HIV hotspots by ...

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. It mostly affects the lungs and is mainly spread through the air between people. Not everyone who is ...