HDAC Inhibitor Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies by DelveInsight
DelveInsight’s, “HDAC Inhibitor Pipeline Insight” report provides comprehensive insights about 40+ companies and 50+ pipeline ...
eLife4d
Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors
However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...
Frontiers23d
The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis
Elevation of miR-206 and further reduction of Akt/mTOR (similar to breast cancer) and reduction of cytosolic Bad and further reduction of 14–3-3 proteins and induction of apoptosis are two mechanisms ...
News Medical27d
Researchers identify a natural defense against blood vessel inflammation and atherosclerosis
A study published in Nature Cardiovascular Research identifies an intrinsic anti-inflammatory ... chemotherapeutic drug resistance, apoptosis resistance, and nuclear-cytoplasmic transport.