A Kolkata teacher beats Stage IV ovarian cancer with advanced surgery, genetic testing, and targeted therapy—while inspiring ...

Researchers have made a major breakthrough in understanding the origins of one of the deadliest forms of ovarian cancer, ...

Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression, Cancer Cell, June 2025 DOI: (25)00253-3 ...

A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer—and offers a potential pathway for new treatments. High-grade serous carcinoma, the most common ...

BOSTON — Patients with non- BRCA gene mutations undergoing risk-reduction surgery to prevent tubo-ovarian cancers showed no signs of tubo-ovarian high-grade serous carcinoma or serous tubal ...

“High-grade serous ovarian carcinoma (HGSOC) is the most common ovarian cancer subtype, with more than 70% of patients presenting with metastatic disease at the time of diagnosis,” the authors ...

Study reveals that high-grade serous carcinoma, the most aggressive form of ovarian cancer, originates from pre-ciliated tubal epithelial cells in the fallopian tube. This research provides insights ...

Low-grade serous ovarian cancer (LGSOC) presents differently than the more common high-grade serous carcinoma. It tends to show up in younger people, grows slowly, and has higher survival rates.

But in general, doctors consider epithelial ovarian cancer to be aggressive. This is because high grade serous epithelial ovarian cancer is very aggressive and makes up the majority of cases.

*For the purposes of this survey, the term LGSOC refers to people diagnosed with low-grade serous carcinoma of the ovary or peritoneum (the thin layer of tissue lining the abdomen).

Ovarian cancer is the most common cause of mortality in patients with gynecologic malignancies. Advanced-stage high-grade serous carcinoma (HGSC) accounts for most ovarian cancer cases.

The prognosis is particularly poor in ovarian high grade serous carcinoma (HGSC), a subtype of ovarian cancer. Less than 40% of patients with this subtype survive five years after their diagnosis.