How the US organ transplant system works and what to ask to improve your chances

By LAURAN NEERGAARD It’s not always patience and luck that get patients off the organ transplant waiting list and into the ...

AI Can Design Antibodies Faster Than Anyone Can Check Them for Immune Risk. That Gap Is Starting to Close.

When the body treats a therapeutic antibody as foreign, it produces anti-drug antibodies that can blunt the drug’s effect, change how it moves through the body and raise safety concerns. The FDA’s ...

UL Solutions Introduces Certification Pathway for DC Energy Storage Systems, Simplifying Reviews of Modular Installations

UL Solutions (NYSE: ULS), a global leader in applied safety science, today announced a new certification pathway designed to help manufacturers of modular direct current (DC) energy storage systems, ...
GitHub

ai-systems-design

3-tier persistent memory for AI agents. Hot Redis cache → warm semantic vector search → cold SQLite. Automatically promotes frequently accessed memories and demotes stale ones. Works with or without ...

CedarDB wants one database to handle both transactions and analytics, as AI agents raise the stakes

Databases have traditionally been designed either for analytical data or for operational data. But database engine CedarDB ...

Researchers use AI to design proteins that cut up other proteins

But in Earth’s environment, most proteins don’t last nearly that long. That’s because organisms have evolved a handful of ...
GitHub

ai-system-design

System Design explained from first principles to senior engineer-level thinking, with a focus on AI-assisted (vibecoding) development. Learn how to reason about systems, understand trade-offs, and ...
Nature

In the AI era, coding means thinking like a systems architect

Now, anyone can prompt an AI model to construct complex computational pipelines that would otherwise require days or weeks of ...
BIOENGINEER

How Your Database Architecture Shapes the Way Machines Tell Records Apart

A comprehensive new review argues that database architecture, not just algorithms, determines how successfully entity ...

Design Systems Won’t Save Bad Strategy

Many companies begin systems work with an audit. They find five versions of a card, three navigation patterns and several ways to present the same type of information. The natural response is to ...
Unite.AI

What Is a Vector Database? How AI Stores and Searches Embeddings

Vector databases store, index, filter, and search embeddings so applications can retrieve items by similarity at operational scale. This guide explains the mechanism, trade-offs, evaluation, and ...
NPR

The Supreme Court revives a controversial data system for citizenship checks

The U.S. Supreme Court has for now revived a federal data system the Department of Homeland Security revamped into a tool to check the citizenship of millions of Americans on state voter rolls. The ...