Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature Communications, a multi-institutional research team including The University of Osaka ...

Scientists at Southern University of Science and Technology in Shenzhen, China, have identified a new regulator of the mammalian target of rapamycin (mTOR) pathway associated with the growth of ...

Colon cancer has been on the rise in Americans under 50 for the last three decades, but it’s not exactly clear why. Researchers suspect poor diet, obesity, sedentary lifestyles, environmental ...

Vitamin D’s anti-cancer powers go beyond bones, new findings reveal how it suppresses inflammation, boosts immune surveillance, and disrupts tumor development to guard against colorectal cancer. Study ...

Justin Stebbing does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

In healthy colon tissue, "good" fibroblasts help support tissue architecture. However, in colon cancer, these fibroblasts transform into "bad" fibroblasts in low-oxygen areas near the tumor surface.