For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer’s disease and other ...

However, cell senescence is one process which appears to play a significant role in bringing on the negative consequences of getting older. Professor Richard Faragher, an expert on cell ageing ...

F. Passos et al., "Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence," PLoS Biology, 5:1138, 2007. (Cited in 31 papers) The study: To investigate why ...

Immortalized cell lines are derived from cancer cells or genetically modified to overcome senescence, allowing them to proliferate ... and disease modeling. 3D cell cultures involve growing cells in a ...