The islets of Langerhans are the regions of the pancreas that contain cells that produce hormones. There are five types of cells in the islets of Langerhans: beta cells secrete insulin; alpha ...

In a clinical trial led by University of Toronto researchers, an allogeneic stem cell–derived islet therapy (zimislecel) ...

Dr. Perrier: "We are getting closer to the goal of developing a standard treatment for diabetes that could one day make ...

To investigate the mechanisms of beta cell loss in T2D, researchers at the DZD performed single-cell RNA sequencing of islets of Langerhans in two obese mouse strains that differ in their ...

Beta cells are cells in the pancreas. They are found in groups called islets. Beta cells create insulin, a hormone that regulates your blood glucose levels. When your blood glucose levels increase ...

Insulin-producing cells, also called beta cells, are located in regions of the pancreas called islets of Langerhans.They are present in clusters of cells that produce other hormones involved in ...

image: (top left and right) Two different ways in which islet cell loss can be observed. (bottom left) The relationship between the percentage of pancreatic beta cells and islet cell loss.

While other mechanisms for beta cell loss need to be considered, these findings also seem to suggest that the phenomenon of islet cell loss may be a key driver of senile diabetes.

A pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a ...

Sander now plans to use vascularized SC-islet organoid models to study Type-1 diabetes, which is caused by immune cells attacking and destroying beta cells in the pancreas – in contrast to Type ...

They transplanted human islets containing beta cells into the kidneys of live mice that lacked an immune system. For 3 months, the scientists gave the mice harmine and exendin-4.

One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...