The addition of the aldosterone synthase inhibitor helped lower blood pressure in patients with resistant hypertension.

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...

However, this contributes to the pathology of the disease by, among other actions, increasing the release of aldosterone. Aldosterone has been shown to cause coronary inflammation, cardiac ...

In March 2025, Shandong Suncadia Medicine Co., Ltd. conducted a phase II Clinical Study of Efficacy and Safety of HRS-1780 ...

Both insulin resistance and obesity have substantial effects on aldosterone action; 7,8 hence, the prevalence of these conditions in a study population might influence the clinical response to ...