Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...

Several seminal studies published in Gut have demonstrated a strong association between dysfunctional sucrase-isomaltase (SI) ...

Early broadly neutralising antibody responses against the E1E2 glycoprotein seem to be important for preventing persistence ...

Endoscopic submucosal dissection (ESD) enables en bloc resection for early gastrointestinal malignancies but is technically ...

Background Gastric cancer (GC) ranks among the most prevalent lethal tumours globally. Cancer-associated fibroblasts (CAFs) are pivotal in creating an immunosuppressive tumour microenvironment (TME) ...

Correspondence to Professor Jun Li, Laboratory for Diagnosisand Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First ...

Background and aims The crosstalk between cancer stem cells (CSCs) and their niche is required for the maintenance of stem cell-like phenotypes of CSCs. Here, we identified E26 transformation-specific ...

Background Covid-19 Induced Hepatitis (CIH), is a novel terminology which is used in this article for the first time in the medical literature. Objective To study the pattern of liver impairment in ...

Objectives Existing scores are not accurate at predicting mortality in upper (UGIB) and lower (LGIB) gastrointestinal bleeding. We aimed to develop and validate a new pre-endoscopy score for ...

The serum levels of conjugates of chenodeoxycholic acid (chenyl conjugates) and of cholic acid (cholyl conjugates) were determined by specific radioimmunoassays during a 24-hour period, which included ...

Dr A Fasano, Division of Pediatric Gastroenterology and Nutrition, University of Maryland School of Medicine, 685 W Baltimore St HSF Building, Room 465, Baltimore, MD 21201, USA.

Objective Hepatitis D virus (HDV) is a defective virus that completes its life cycle only with hepatitis B virus (HBV). The HBV with HDV super-infection has been considered as one of the most severe ...