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Comparing traditional and AI-enhanced strategies for developing patient decision aids: a multiple case study

Objectives Our objective was to develop and test prompts designed to generate balanced, evidence-based information from artificial intelligence (AI) for the development of patient decision aid (DA) ...
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Reconsidering the role of tramadol in chronic pain management

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Correspondence on 'Less is more for patients, practitioners, public and planet: a taxonomy for the harms of too much medicine

Gram et al ’s taxonomy of the harms of ‘too much medicine’ offers a valuable and timely framework for understanding how medical excess affects patients, practitioners, the public and the planet.1 ...
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Adverse effects of overdiagnosis on our understanding of disease

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How methodological pitfalls have created widespread misunderstanding about long COVID

The existing epidemiological research on long COVID has suffered from overly broad case definitions and a striking absence of control groups, which have led to distortion of risk. The unintended ...
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Using Risk of Bias 2 to assess results from randomised controlled trials: guidance from Cochrane

Correspondence to Dr Kerry Dwan, Centre for Reviews and Dissemination, University of York, York, UK; Kerry.dwan{at}york.ac.uk A systematic review identifies, appraises and synthesises all the ...
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Alcohol and atrial fibrillation: to or not to drink?

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Early experience with the FDA’s regulatory review of novel gene therapies

Correspondence to Dr Jeremy Puthumana, Yale University School of Medicine, New Haven, Connecticut, USA; jeremy.puthumana{at}yale.edu Contributors JP and JR drafted the manuscript. JP and ACE acquired ...
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Diet–heart disease hypothesis is unaffected by results of analysis of recovered data from Minnesota Coronary Experiment

Correspondence to: Professor Murray Skeaff, Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand; murray.skeaff{at}otago.ac.nz If you wish to reuse any or all of ...
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Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression

The efficacy of antidepressants in the acute treatment of moderate-to-severe depression remains a controversial issue. The minimal important difference (MID) is relevant to judge the clinical ...
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Adherence to the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) of studies on evidence-based healthcare e-learning: a cross ...

Correspondence to Dr Tina Poklepović Peričić, Department of Research in Biomedicine and Health, University of Split School of Medicine, Split, Croatia; tinapoklepovic{at}gmail.com Objectives The ...
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EBM Guidelines: Evidence-Based Medicine

This electronic resource aims to provide physicians with fast and easy access to practical guidelines linked to the best available research evidence. It covers a wide range of medical conditions and ...