A study by Children's Medical Research Institute (CMRI) researchers reveals a new group of proteins that guide the powerful enzyme telomerase, opening potential doors to novel treatments for cancer, ...

Dr. Thomas Jankowski explained that THIO, a telomerase inhibitor, is being studied with Libtayo to help overcome resistance in advanced lung cancer.

The biotech is now running a Phase II expansion study to better evaluate the long-term benefits of ateganosine in third-line ...

Study shows how telomerase can run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage. The natural ends of chromosomes appear alarmingly like broken DNA, much as ...

Telomerase activation is considered to be a critical step in cancer progression due to its role in cellular immortalization. The prevalence of telomerase expression in human cancers makes it an ...

The discovery of a vitally important new function for this telomerase inhibitor suggests a novel option for treating cancers of the breast, lung, liver and GI system. It's been nearly 10 years since ...

Of the many components in the cell thought to play a role in cancer, few have received more attention in recent years than an enzyme that has been dubbed a cellular fountain of youth. Known as ...

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a ...

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase. Telomerase's only known role in normal tissue was to protect certain ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

More than 30 years ago, when UC Berkeley researchers discovered telomerase — an enzyme that lengthens chromosome ends and prevents them from fraying enough to kill a cell — speculation ran wild about ...