Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired ...

Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair.. | Cell And Molecular Biology ...

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of ...

A new study led by researchers at the University of Pittsburgh (Pitt) and UPMC Hillman Cancer Center has shown that an enzyme called PARP1 is involved in the repair of telomeres, the lengths of DNA ...

Our genome is organized into chromosomes, which are shaped like little X's. Every time a cell divides, the genome has to be replicated, and there are protective caps called telomeres on the ends of ...

Increased chromosomal instability impairs oocyte quality, contributing to female reproductive aging. The telomeric DNA damage ...

A new study shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere ...

When a cell divides, a small section of the telomere of each chromosome is worn away. While most cells use the enzyme telomerase to mitigate this loss, about 10–15% of cancers use a different ...

One protein appears to play an integral role in protecting telomeres, and possibly preventing cancerous growth, according to a study published this week in Science. Chromosomes with fluorescently ...

Telomere is a repeated sequence (TTAGGG)N that caps the end of the chromosomes to protect them from damage during DNA replication prior to cell division. Telomere length is essential to the cell's ...

Aparna is a freelance science writer with a PhD in bioinformatics and genomics at Harvard University. Her writing has also appeared in The Philadelphia Inquirer, Popular Science, PBS NOVA, and more.