Robust reductions in tau pathology were observed across all studied doses, with results generally consistent with those observed in the Phase 1b ...

A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau. This is the finding of research from the University of Gothenburg, which also offers a ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

In a study published in the Journal of the American Chemical Society, scientists explore how a brain protein called tau changes its behavior when a small chemical group called a phosphate attaches to ...

Newly reported research headed by a team at the Perelman School of Medicine at the University of Pennsylvania points to a potential gene therapy approach to neurodegenerative disorders characterized ...

Share on Pinterest A new study reveals that a particular type of toxic protein, “oligomeric tau,” may play a key role in Alzheimer’s disease. Westend61/Getty Images A new study investigating Alzheimer ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...

On the heels of a June 17 paper showing a small molecule's ability to declutter pathological protein buildups in the brain, researchers from the University of California, San Diego (UCSD) and the ...

Chemists have determined the structure of the fuzzy coat that surrounds tau proteins. Learning more about this structure could help scientists find ways to block tau from forming tangles in the brains ...

Researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau -- which is primarily found in neurons that appear abnormal in the brains of Alzheimer's ...

Researchers have clarified the relationship between the intracellular receptor PQBP1 and the structural protein Tau, which is dysregulated in neurodegenerative diseases such as Alzheimer's disease.

The protein acts as a scaffold, Lasagna-Reeves said; if bassoon is removed, it will make the tau seed more unstable. Martinez said by lowering the level of bassoon in the models, it decreased the ...