DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

Azoospermia is a condition in which sperm cells are completely absent in a male’s ejaculate. Typically, sperm production occurs in the testes and is regulated by a complex series of cellular and ...

Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed -- for instance in ...

Paul Victor, Dhamodharan Umapathy, Leema George, Udyama Juttada, Goutham V. Ganesh, Karan Naresh Amin, Vijay Viswanathan and Kunka Mohanram Ramkumar Increasing evidence in substantiating the roles of ...

Newly discovered mechanism helps detach and recycle parts of cellular canal membranes as needed – models developed using ...