A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural biologists at RIKEN. This could inform the development of new therapies. When ...

For decades, scientists thought the noncoding parts of DNA were useless leftovers. Today, that view has completely changed.

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

Although nanopores are very different from living cells, these kinds of plectonemes may also form during processes like DNA transcription and replication. Transcription describes when DNA's code gets ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development. New research has uncovered more about the complexity of human gene ...

In a remarkable fusion of biology and technology, a DNA-based computer that performs effectively has been created by ...