Fas receptor is a member of the tumor necrosis $factor-\alpha$ family of death receptors that mediate physiologic apoptotic signaling. To investigate the molecular ...

A research team from Kyushu University in Japan has recently discovered a calcium-based mechanism that plays a key role in the disposal of dead cells, shedding light on how our bodies protect ...

Li et al. explain how prolonged stress sparks the endoplasmic reticulum (ER) to release its calcium stores, inducing cells to undergo apoptosis in several aging-related diseases.The study will appear ...

Researchers from Japan have developed novel complex-peptide hybrids, which can induce programmed cell death in apoptosis-resistant cancer cells Apoptosis, a type of programmed cell death (PCD), is a ...

Substance P (SP) regulates multiple biological processes through its high-affinity neurokinin-1 receptor (NK-1R). While the SP/NK-1R signaling axis is involved in the pathogenesis of solid cancer, the ...

Hamilton, ON - Canadian scientists studying the causes of atherosclerosis at the cellular level have shown that nitric oxide (NO) can be converted to peroxynitrite, an agent known to accelerate ...

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression. By analyzing liver ...

For almost a quarter of a century, researchers have been studying and publishing on the effect of calcium on Alzheimer's Disease. Research has led to the development of the calcium hypothesis of ...

Inducing programmed cell death (PCD), such as apoptosis, is a widely used therapeutic option for the treatment of cancer. Unfortunately, many cancer cells become resistant to PCDs, and continue ...