In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria. To function properly, mitochondria must first read ...

A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm. As direct ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

In a study published in Nature Neuroscience, researchers from Inserm and the University of Bordeaux at the NeuroCentre ...

Scientists have found DNA in the nucleus of brain cells, where it shouldn’t be. Bits of genes that typically reside in mitochondria insert themselves at unexpectedly high rates into brain cells’ ...

Scientists at St. Jude Children’s Research Hospital discovered that metabolism controls regulatory T cells, the “brakes” of the immune system (MEMPHIS, Tenn. – October 24, 2025) Metabolism guides the ...

Cancer cells can brainwash their neighbors. Like the CIA deploying secret agents to turn an enemy, tumors use a similar strategy to manipulate nearby cells. The tumors’ agents are mitochondria, the ...

Mitochondria release segments of mitochondrial DNA that can travel through pores of the nucleus and integrate into a cell's chromosomes (where the insertions are called NUMTs, for nuclear ...

Researchers have shown for the first time that malfunctioning mitochondria — the cell’s energy generators — may directly ...