Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics.

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites ...

Pyruvate dictates redox balance and cell size, establishing metabolism as a dominant regulator of cellular fitness, unveiling new strategies to modulate cancer, regeneration, and diabetes.

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative ...

Jagged-2, a signaling protein, may be a potential therapeutic target for slowing or halting the progression of PAH, according ...

T cells are part of the immune system that protects the body from infection by reacting against foreign or self-antigens via ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...