Researchers at the University of Greifswald have discovered a new mechanism by which bacteria such as Bacillus subtilis can regulate the production of the central metabolic molecule acetyl coenzyme A ...

The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...

Insufficient acetyl-CoA derails the immune system's ability to protect the body. Until now, however, it was unclear exactly how immune cells maintained their acetyl-CoA reserves. In their new study, ...

A peer-reviewed review identifies altered lipid uptake, synthesis, oxidation and storage as drivers of hepatocellular carcinoma and possible therapeutic targets, while warning that clinical evidence ...

2-Jul-2025 at 6:05 AM EDT, by Chinese Academy of Sciences The study also demonstrated that the disruption in citric acid cycle and reduction in acetyl CoA and pyruvate contents contributed to ...