Scientists have revealed how the electrical patterns formed within an embryo initiate a cascade of molecular changes that culminate in the development of cartilage and bone. Prior studies have shown ...

The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.

Scientists now have a better picture of how voltage-gated sodium (Na v) channels interact with certain animal toxins, thanks to structures solved with cryo-electron microscopy. These channels are ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

A new study in the Journal of General Physiology (http://www.jgp.org) provides fresh insight into voltage-gated channels—transmembrane ion channels that play a ...

The voltage-gated potassium (Kv) channel Kv1.5 mediates the ${\rm I}_{{\rm Kur}}$ repolarizing current in human atrial myocytes and regulates vascular tone in multiple peripheral vascular beds.

Voltage-gated potassium (Kv) channels play an important role in modulating the electrical activity of cells, opening in response to changes in membrane voltage and allowing potassium ions to escape.

Shanghai Aryl Pharmtech Co. Ltd. and Zhejiang Hisun Pharmaceutical Co. Ltd. have jointly patented new potassium voltage-gated channel subfamily A member 3 (KCNA3; Kv1.3) blockers for use in the ...

image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...