In a study published in Nature Communications, Lewis Zhichang Shi, M.D., Ph.D., and University of Alabama at Birmingham colleagues show, for the first time, how HIF1α in T cells is key for induction ...

Hydrogen sulfide can effectively reverse established hypoxia-induced PH and remodeling of pulmonary vascular structure in a rat model.

Right ventricular (RV) remodeling and dysfunction are serious cardiovascular consequences due to prolonged hypoxic exposure, commonly seen in conditions such as chronic lung disease and high-altitude ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders ...