During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Mitochondrial ribosomes, or mitoribosomes, are specialised organellar complexes responsible for synthesising a subset of proteins encoded by mitochondrial DNA. These proteins are critical for the ...

Mammalian cells dynamically scale translation initiation to match distinct elongation rates, preventing ribosome crowding and preserving protein synthesis homeostasis across diverse transcripts.

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

Slower ribosomes stall during translation and collide with faster ones, triggering selective degradation of their small subunits. This “ribosome competition” mechanism ensures that only efficient ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

A pink ribosome surrounds part of a red-and-yellow helix-shaped strand of messenger RNA while a yellow protein branch extends from the ribosome. A graphic representation of a ribosome (pink) ...

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

Ribosomes are molecular machines that translate messenger RNA (mRNA), which is transcribed from DNA, into proteins. Scientists have now learned more about ribosomes in nature, and their function. This ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...