Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on ...

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...

New research published in Immunity by researchers at the University of Pittsburgh found that, in mice, the toxic tumor ...

Vitamin D is one that has found itself in the spotlight often in recent years. Also known as the "sunshine vitamin", it has ...

Telomeres are the "caps" that protect the ends of DNA strands from being destroyed by a cell. They are made up of areas of repeated DNA sequences combined with specific proteins at the ends of ...

New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1. The length of ...

Henagliflozin, a popular drug prescribed for type 2 diabetes, has demonstrated potential anti-aging effects in a recent study ...

Longer leukocyte telomere length is associated with higher left ventricular mass (LVM) and larger global ventricular size, as well as better cardiac function and lower risk of heart failure (HF). The ...

In an advance in legume genomics, researchers from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences have produced the first gap-free, telomere-to-telomere ...

CST (purple/lavender) bound to POT1 (red). Phosphorylation of the crimson-highlighted region in POT1 regulates the recruitment and activity of CST–Polα-primase at telomeres. The length of telomeres ...