Barth syndrome is a rare genetic disorder caused by mutations in the TAZ gene, which encodes an enzyme essential for remodeling cardiolipin, critical for mitochondrial function. A recent study ...

Researchers at The Hospital for Sick Children (SickKids) have uncovered a promising new therapeutic target for Barth syndrome ...

These findings suggest a promising new approach to neurotherapeutics that targets the underlying mechanisms of diseases like Parkinson’s and Alzheimer’s, rather than just managing symptoms. The study ...

They fall into the following main categories: mitochondria-targeted antioxidants, modulating mitochondrial dynamics, enhancing mitochondrial quality control, potentiating mitochondrial biogenesis, ...

Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.

Researchers from Inserm and the University of Bordeaux, in collaboration with the University of Moncton, have developed an ...

Aging can seem like an unregulated process: As time marches along, our cells and bodies inevitably accumulate dings and dents that cause dysfunctions, failures, and ultimately death. However, in 1993 ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion ...