In the last five years evidence of an autoimmune response in pernicious anemia has been presented. Circulating antibodies to both gastric intrinsic factor and to the cytoplasm of gastric parietal ...

Intrinsic factor antibodies: This records levels of intrinsic factor antibodies. The doctor may also carry out a bone marrow test. The two types of bone marrow test are an aspiration or a biopsy.

Are you lacking the intrinsic factor? It’s one of the causes of vitamin B12 deficiency, explains nutritionist Louise Pyne The Standard's journalism is supported by our readers.

Stomach acid and the enzyme pepsin help release it during digestion. Once free, B12 binds to an intrinsic factor, a protein produced by the stomach lining. This complex protects B12 as it moves ...

Some people don’t make enough of this protein, or suffer from an autoimmune condition like Crohn’s disease or pernicious anaemia which cause you to stop making intrinsic factor. In these conditions, ...

Parietal cells secrete hydrochloric acid that helps break down food and intrinsic factor that aids in the absorption of vitamin B12. Chief cells secrete enzymes that support digestion.