When a rogue cell starts proliferating out of control, the first responders on the scene should be the body’s own immune cells—for example, natural killer (NK) cells, which use toxic molecules to ...

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and refractory cases continuing to pose significant hurdles. Traditional therapies ...

Natural Killer (NK) cells are vital immune defenders that target and destroy cancer cells. However, in aging and cancer patients, NK cells often become "senescent"—losing their effectiveness due to ...

A team led by Prof. TIAN Zhigang and Prof. PENG Hui from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. ZHANG Zemin from ...

Researchers at The University of Texas MD Anderson Cancer Center have developed the first genome-wide CRISPR screening platform tailored for primary human natural killer (NK) cells. The tool, called ...

Immune evasion continues to limit the effectiveness of cancer immunotherapies. Among emerging regulatory molecules, transfer RNA-derived small RNAs (tsRNAs of 13-48 nucleotides), generated through ...

Research, headed by teams at Trinity College Dublin and University College Dublin, has uncovered how lipid-rich fluid in the abdomen, known as ascites, plays a central role in weakening the body’s ...