When designing a nanoparticle-enabled drug delivery system, many intersecting considerations must be taken into account, such as the target location of the drug payload, the method of delivery, uptake ...

Pharmaceutical scientists and biologists are teaming up to make the next generation of lipid nanoparticles (LNPs) for drug delivery. Combining structural biology with cutting edge pharmaceutical ...

Scientists at Xi'an Jiaotong-Liverpool University (XJTLU) and Nanjing University in China have developed a new drug delivery system that could improve how treatments of cancers and other diseases are ...

Researchers have turned to drug delivery nanoparticles to maximize the anti-cancer STING of a molecule, pointing to a possible way to unlock the potential of a pathway that has caught the eye of the ...

Research published last month in the journal Molecular Pharmaceutics details a new mechanism for delivering pancreatic cancer drugs to tumors. The research, carried out by a team from Kansas City ...

DDS can be based on physical mechanisms like osmosis, diffusion, erosion, dissolution, and electro-transport or biochemical methods like monoclonal antibodies, gene therapy, vector systems, ...

Polymeric nanoparticles are nanoscale particles composed of natural or synthetic polymers, typically ranging in size from 10 to 1000 nanometers. These nanoparticles have gained significant attention ...

A new nanoparticle made from the medical polymer PLGA and the blood protein albumin can carry higher doses of drugs and remain stable longer, offering improved delivery and fewer side effects. For ...

Use of the delivery system in mouse models results in unprecedented siRNA penetration across the intact blood brain barrier Technology could offer potential for a variety of human neurological ...

A major breakthrough in cancer drug delivery took place in 1995, when the FDA approved the first nanodrug, Doxil—a liposomal formulation of doxorubicin engineered to preferentially accumulate in ...

To facilitate successful delivery of therapeutic agents to the brain, a team of bioengineers and physicians created a nanoparticle platform, which can facilitate therapeutically effective delivery of ...