A 2026 review identifies pyroptosis as a context-dependent pathway in intestinal and systemic inflammation and evaluates ...

Inflammaging is a state of persistent, low-grade inflammation associated with aging, influenced by immune dysfunction, ...

A new study published in The American Journal of Pathology provides new evidence that immune cells enter the retina via the body's standard pathway, identifying PECAM as the gatekeeper and neutrophils ...

The immunomodulatory effects of mesenchymal stem cells (MSCs) on macrophages have been reported, however, the underlying mechanism remains unknown. Therefore, this study aimed to investigate the ...

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein ...

A study led by the Innovation in Vesicles and Cells for Application in Therapy (IVECAT) group at the Germans Trias i Pujol Research Institute (IGTP) has identified a key mechanism regulating the ...

New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's disease. A research team led by Mount Sinai has uncovered mechanisms of ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...

The inflammatory response is vital for fighting off infections, but too much inflammation can damage the body tissues and cause a variety of disorders. Fortunately, our immune cells have a procedure ...

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to ...

Jessica Rendall is a reporter with experience covering a variety of health and wellness topics, including chronic disease, infectious disease, telemedicine, mental health and health technology. Carley ...